A next-generation oral peptide that supports tendon, ligament, and soft tissue repair in the foot and ankle — without injections, without downtime.
Synapep uses lactoferrin conjugation and liposomal protection to deliver BPC-157 through the digestive tract — protecting the peptide from stomach acid and maximizing absorption.
amino acid peptide chain
downtime or recovery
BPC-157 is a 15-amino-acid peptide derived from a naturally occurring protein in the stomach. Synapep is a physician-grade formulation that makes this peptide available orally for the first time — using a patented delivery system designed specifically for soft tissue healing.
BPC-157 — short for Body Protection Compound 157 — was first studied for gastrointestinal conditions, where it showed a remarkable ability to accelerate mucosal healing. Researchers then discovered these same tissue-repair properties extend throughout the musculoskeletal system, including the tendons, ligaments, and cartilage of the foot and ankle.
Traditionally, BPC-157 required subcutaneous injection to be effective. Synapep changes that by conjugating the peptide to lactoferrin — a natural carrier protein — which allows it to survive digestion and absorb through the lining of the mouth and intestines directly into the bloodstream.
At Foot & Ankle Specialists of Ames, Dr. Nelson offers Synapep as part of a broader regenerative strategy for patients dealing with chronic soft tissue pain, stalled healing, and conditions that haven’t responded fully to conservative care.
BPC-157 works through multiple biological pathways simultaneously — which is why it can be effective where single-mechanism treatments fall short.
BPC-157 stimulates the body’s natural regenerative processes, helping tendons and ligaments move through the stages of healing more efficiently — particularly in tissue that has stalled in chronic inflammation.
By modulating inflammatory cytokines, BPC-157 helps interrupt the cycle of persistent inflammation that keeps many foot and ankle conditions from fully resolving — including Achilles tendinitis and plantar fasciitis.
Collagen is the primary structural protein in tendons and ligaments. BPC-157 upregulates collagen synthesis to repair and reinforce damaged connective tissues in the foot and ankle.
The foot and ankle have notoriously limited circulation, which slows healing. BPC-157 supports angiogenesis — the formation of new blood vessels — improving nutrient delivery to injured tissue.
Fibroblasts are the cells responsible for building connective tissue. BPC-157 enhances their activity and migration to injury sites, making it especially useful as an adjunct to PRP or laser therapy.
Pre-dosed oral sachets make Synapep straightforward to use at home. No clinic visits, no needles, no complicated protocols — just a simple part of your daily recovery routine.
Dr. Nelson may recommend Synapep BPC-157 for patients with the following diagnoses — particularly when initial conservative treatment hasn’t produced full resolution.
Synapep works best as part of a thoughtful treatment plan. Dr. Nelson will evaluate your history and imaging to determine if it’s the right fit.
Synapep is often used alongside other in-office therapies at FAS-Ames to amplify and extend healing between visits.
Stimulates cellular energy and circulation, complementing BPC-157’s angiogenic effects.
Starting Synapep is straightforward. Here’s what a typical course of therapy looks like from your first visit.
Dr. Nelson reviews your history, conducts a physical exam, and may use diagnostic ultrasound or imaging to assess the extent of tissue damage and determine if Synapep is appropriate for your case.
If Synapep is recommended, Dr. Nelson will outline how it fits into your broader treatment strategy — including any in-office therapies, orthotics, or activity modifications that go alongside it.
Synapep is taken at home using pre-dosed sachets. Dr. Nelson will schedule follow-up visits to monitor your response, adjust the plan as needed, and track your recovery progress.
Schedule your consultation today to discover how we can help alleviate your fat pad atrophy symptoms and get you back to the activities you love.
Call the Foot & Ankle Specialists of Ames at (515) 444-2390 or email info@fas-ames.com to make an appointment!
